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From Innate Immunity to Immunological Memory

The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This phenomenon known as "immunological memory", is the foundation upon which the concept if vaccination rests. Therefore, understanding the mechanisms by which immunological memory is regulated is of paramount importance. Recent advances in immunology, particularly in the field of innate immunity, suggest that the innate immune system plays fundamental roles in influencing immunological memory. Indeed, emerging evidence suggests that events that occur early, within hours if not minutes of pathogen or vaccine entry profoundly shape the quantity, quality and duration of immunological memory. The present volume assembles a collection of essays from leading experts that span the entire spectrum research from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses.

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Produktbeschreibung

The ability to remember an antigenic encounter for several decades, even for a life time, is one of the fundamental properties of the immune system. This phenomenon known as "immunological memory", is the foundation upon which the concept if vaccination rests. Therefore, understanding the mechanisms by which immunological memory is regulated is of paramount importance. Recent advances in immunology, particularly in the field of innate immunity, suggest that the innate immune system plays fundamental roles in influencing immunological memory. Indeed, emerging evidence suggests that events that occur early, within hours if not minutes of pathogen or vaccine entry profoundly shape the quantity, quality and duration of immunological memory. The present volume assembles a collection of essays from leading experts that span the entire spectrum research from understanding the molecular mechanisms of innate immune recognition, to dendritic cell function, to the generation and maintenance of antigen-specific B and T-cell responses. 

Inhaltsverzeichnis

TLR Signaling.- Dendritic Cells: Translating Innate to Adaptive Immunity.- Helper T Cell-Regulated B Cell Immunity.- T Cell Memory.- The Privacy of T Cell Memory to Viruses.- Enhancement of Infectious Disease Vaccines Through TLR9-Dependent Recognition of CpG DNA. 

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Produktdetails

Medium: Buch
Format: Gebunden
Seiten: 196
Sprache: Englisch
Erschienen: September 2006
Auflage: 2006
Maße: 241 x 160 mm
Gewicht: 501 g
ISBN-10: 3540326359
ISBN-13: 9783540326359

Bestell-Nr.: 2720600 
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KNO: 15748116
KNO-EK*: 78.71 € (25%)
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KNO-MS: 18

KNO-SAMMLUNG: Current Topics in Microbiology and Immunology Vol.311
KNOABBVERMERK: 2006. x, 184 S. X, 184 p. 13 illus., 12 illus. in color. 235 mm
KNOMITARBEITER: Ed. by Bali Pulendran and Rafi Ahmed
Einband: Gebunden
Auflage: 2006
Sprache: Englisch
Beilage(n): HC runder Rücken kaschiert

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