Encyclopedia of Immunotoxicology

Produktbeschreibung

This work provides rapid access to focused information on topics of Immunotoxicology not only for scientists and those dealing with laboratory aspects but also for lecturers and advanced students. Over 200 contributing authors - including many of the world's top specialists - have contributed full essays on all relevant topics, supplemented by keyword definitions of related terms. Full essays are structured uniformly to provide reader-friendly information on all aspects of Immunotoxicology, including methods of testing and analysis, characteristics of substances, the regulatory environment and the relevance of these to humans. 

Inhaltsverzeichnis

AB0 Blood Group System.- Aging and the Immune System.- Animal Models for
Respiratory Hypersensitivity.- Animal Models of Immunodeficiency.-
Anti-Inflammatory (Nonsteroidal) Drugs.-

Antibodies, Antigenicity of.- Antibody-Dependent Cellular Cytotoxicity.- Antigen
Presentation via MHC Class II Molecules.- Antigen-Presenting Cell (APC).-
Antigen-Specific Cell Enrichment.- Antiglobulin (Coombs) Test.- Antinuclear
Antibodies.- Apoptosis.- Assays for Antibody Production.-

Asthma.- Atopic Allergy.- Attenuated Organisms as Vaccines.- Autoantibodies,
Tests for Autoantigens.- Autoimmune Disease, Animal Models.- Autoimmunity,
Autoimmune Diseases.-

B Cell Maturation and Immunological Memory.- B Lymphocytes.- Biological drugs,
immunosuppression and modulation.- Birth Defects, Immune Protection Against.-
Blood Coagulation.- Bone Marrow and Hematopoiesis.- Brain-Immune Interactions.-
Cancer and the Immune System.- Canine Immune System.- Carcinogenesis.- Cardiac
Disease, Autoimmune

Cat immune system.- CD Markers.- Cell Adhesion Molecules.- Cell Separation
Techniques.-

Cell-Mediated Lysis.- Chemical Structure and the Generation of an Allergic
Reaction.- Chemokines.-

Chemotaxis of Neutrophils.- Chromium and the Immune System.- Chronic Beryllium
Disease.-

Clinical consequence of immunosuppression.- Colony-Forming Unit Assay: Methods
and Implications.- Complement and Allergy.- Complement Deficiencies.- Complement
System.-

Contact Hypersensitivity.- Cyclosporin A.- Cytokine Assays.- Cytokine Genes and
Immunotoxicology, Genetic variations.- Cytokine Inhibitors.- Cytokine
Receptors.- Cytokines.- Cytotoxic T Lymphocytes.-

Cytotoxicity Assays.- Delayed-Type Hypersensitivity.- Dermatological
Infections.- Developmental Immunotoxicology.- Diabetes and Diabetes Combined
with Hypertension, Experimental Models for

Dioxins and the Immune System.- DNA Vaccines.- Drugs, Allergy to.- ELISPOT
Assay.- Enzyme-Linked Immunospot Assay (ELISPOT).- Epidemiological
Investigations.- Erythropoietin.- Exposure Route and Respiratory
Hypersensitivity.- Fatty Acids and the Immune System.- Fish Immune System.-

Flow Cytometry Technique.- Food Allergy.- Germinal Center.- Glucocorticoids.-
Graft-Versus-Host Reaction.- Granuloma.- Guinea Pig Assays for Sensitization
Testing.- Hapten and Carrier Helper T Lymphocytes.- Hematopoietic Stem Cells.-
Hemolytic Anemia, Autoimmune.- Hepatic Immune System.- Hepatitis, Autoimmune.-
Histopathology of the Immune System, Enhanced Host Resistance Assays.- Human
artificial lymph node (hALN).- Human microbiome.- Humanized Monoclonal
Antibodies.- Humoral Immunity.- Hypergammaglobulinemia.- Hypersensitivity
Reactions.-

Idiotype Network.- IgE-Mediated Allergies.- Immune Cells, Recruitment and
Localization of

Immune Complexes and Complement Activation.- Immune Function Assessment for Risk
Assessment in Drug and Registration (Industry, Agro-) Chemicals, Relevance of
Immune Response.- Immunoassays.- Immunoglobulin. Subclasses and Functions.-
Immunopathology.- Immunotoxic Agents into the Body, Entry of.-
Immunotoxicological Evaluation of Therapeutic Cytokines.-

Immunotoxicology.- Immunotoxicology of Biotechnology-Derived Pharmaceuticals.-
Immunotoxicology, in silico analyses.- Immunotoxicology, view of the future.- In
vitro PFCA (MD cultures).- Inbred Strains.- Inflammatory Reactions, Acute Versus
Chronic.- Interferon-γ

Interleukin-1β (IL-1β).- International Collaborative Studies on the Detection of
Immunotoxicity.- Klebsiella, Infection and Immunity.- Knockout, Genetic.-
Leukemia.-

Leukocyte Culture: Considerations for In Vitro Culture of T cells in
Immunotoxicological Studies.-

Limiting Dilution Analysis.- LMW drugs, immunosuppression and modulation.- Local
Lymph Node Assay.- Local Lymph Node Assay (IMDS), Modifications.- Lymph Nodes.-
Lymph Transport and Lymphatic System.- Lymphocyte Proliferation.- Lymphocyte
Transformation Test.- Lymphocytes

Lymphoma.- Macrophage Activation.- Mast Cells.- Maturation of the Immune
Response.-

Memory, Immunological.- Metabolism, Role in Immunotoxicity.- Metals and
Autoimmune Disease.-

MHC Class I Antigen Presentation.- Mitogen-Stimulated Lymphocyte Response.-
Mixed Lymphocyte Reaction.- Molecular Mimicry.- .- Monoclonal Antibodies.- Mouse
Ear Swelling Test.- Mucosa-Associated Lymphoid Tissue.- Natural Antibodies.-
Natural Killer Cell Assay.- Natural Killer Cells

Neonatal Immune Response.- Neutrophil.- Nonhuman Primates, Immunotoxicity
Assessment of (Bio)Pharmaceuticals in Nutrition and the Immune System.-
Opsonization and Phagocytosis.-

Oral Mucositis and Immunotoxicology.- Pharmacokinetics and Pharmacodynamics of
Therapeutic Monoclonal Antibodies.- Photoreactions.- Photoreactive Compounds.-
Plaque Versus ELISA Assays. Evaluation of Humoral Immune Responses to
T-Dependent Antigens.- Plaque-Forming Cell Assays.-

Polychlorinated Biphenyls and the Immune System.- Polyclonal Activators.-
Polycyclic Aromatic Hydrocarbons and the Immune System.- Polymerase Chain
Reaction.- Popliteal Lymph Node Assay.-

Popliteal Lymph Node Assay, Secondary Reaction.- Porcine Immune System.- Primate
Immune System (Nonhuman) and Environmental Contaminants.- Prostaglandins.-
Rabbit Immune System.-

REACH and Immunotoxicology.- Regulatory Environment.- Regulatory Guidance in
Immunotoxicology.- Relative Risk.- Reporter Antigen Popliteal Lymph Node Assay.-
Respiratory Infections.- Rheumatoid Arthritis and Related Autoimmune Diseases,
Animal Models.- Rodent Immune System, Development of the.- Rodents, Inbred
Strains.- Salmonella, Assessment of Infection Risk.- Septic Shock.- Serotonin.-
Serum Sickness.- Signal Transduction During Lymphocyte Activation.- Skin,
Contribution to Immunity.- Southern and Northern Blotting.- Spleen.- Statistics
in Immunotoxicology.- Steroid Hormones and their Effect on the Immune System.-
Streptococcus Infection and Immunity.- Stress and the Immune System.-
Superantigens.- Suppressor Cells

Systemic Autoimmunity.- T Regulator Cells.- TDAR Update for NHP Immunotoxicity
Studies

Tests for Autoimmunity.- TH17 Cells.- Three-Dimensional Human Skin, Epidermal
Models and Organotypic Human and Murine Skin Explant Systems.- Thymus.- Thymus:
A Mediator of T Cell Development and Potential Target of Toxicological Agents.-
Tolerance.- Toxicogenomics, Microarray Technology.- Trace Metals and the Immune
System.- Transforming Growth Factor β1; Control of T Cell Responses to
Antigens.- Transgenic Animals.- Trypanosomes, Infection and Immunity.-

Tumor Necrosis Factor-α.- Tumor, Immune Response to.- Vaccines therapeutic.-
Vanadium and the Immune System.- Viability, Cell.- Vitamins.- Western Blot
Analysis. 

Autoreninfo

Dr. Vohr is working as "Senior Expert" for immunotoxicology with global responsibility for Bayer HealthCare AG, and is a member of various international expert councils for immunotoxicology and photoreactions.